Authors Selventhiran Rengaraj focuses on technical program management and solution delivery for Smart City, Smart Health, and Industry 4.0. He brings hands-on experience in developing robotics stacks for ground and underwater robots, specializing in optimizing advanced AI and perception systems across leading semiconductor platforms for embedded applications.
Rabiya S A Bhaimia drives marketing initiatives for Smart City, Smart Health, and Industry 4.0, focusing on campaigns, content, and outreach strategies that communicate value to global audiences.
Introduction
Artificial intelligence is profoundly redefining medical imaging. From radiology to pathology, deep learning now powers everything from anomaly detection in CT scans to cancer grading on digital slides. At the center of this evolution is MONAI (Medical Open Network for AI) an open-source, PyTorch-based framework that has quickly become the industry’s backbone for developing state-of-the-art medical imaging AI models.
MONAI brings structure and standardization to an ecosystem limited by siloed pipelines and fragmented toolkits. It streamlines data loading, preprocessing, augmentation, segmentation, and deployment. It is why researchers, startups, and major health institutions alike are building their pipelines on MONAI.
Despite MONAI’s strengths, real-world deployment poses distinct challenges. Hospitals and device manufacturers often do not operate in GPU-rich research labs; they need low-latency, cost-efficient, clinically reliable AI inference on constrained hardware.
And that is the gap where MulticoreWare is pushing the boundary.
MONAI: The AI Standard for Medical Imaging
MONAI is an open-source, community-driven ecosystem spearheaded by NVIDIA and academic contributors that is rapidly becoming the healthcare equivalent of Hugging Face, offering a unified platform for building, sharing, and deploying medical imaging AI. Its strengths include:
Task coverage
Supports Segmentation (e.g., organs, tumors), classification (e.g., disease presence, severity grading), detection (e.g., fractures, nodules), registration (e.g., image alignment)
Data formats
DICOM (Digital Imaging and Communications in Medicine), NIfTI (Neuroimaging Informatics Technology Initiative), and WSI (Whole Slide Imaging) support out of the box
Modules
MONAI Label for interactive annotation, Auto3DSeg for automated segmentation, MONAI Deploy for packaging & deployment.
Future-ready
Extensible for multimodal systems that combine imaging, language, and clinical workflows
With these capabilities, MONAI has become the research gold standard for CT, MRI, ultrasound, and pathology models.


The Deployment Gap: From Lab Models to Clinical Reality
While MONAI-trained models show state-of-the-art accuracy, they often demand:
- Multi-GPU clusters (powerful GPUs like A100 80GB)
- High memory bandwidth
- Long inference times (seconds → minutes for 3D segmentation)
Meanwhile, clinical systems often demand:
- Real-time inference (sub-second latency for critical workflows)
- Compact footprints on portable ultrasound machines, mobile X-ray, or hospital edge servers
- Power efficiency for continuous operation in constrained environments
The trade-off between model sophistication and clinical practicality represents the primary bottleneck in the adoption of medical AI today.
The Deployment Gap: From Lab Models to Clinical Reality
While MONAI-trained models show state-of-the-art accuracy, they often demand:
- Multi-GPU clusters (powerful GPUs like A100 80GB)
- High memory bandwidth
- Long inference times (seconds → minutes for 3D segmentation)
Meanwhile, clinical systems often demand:
- Real-time inference (sub-second latency for critical workflows)
- Compact footprints on portable ultrasound machines, mobile X-ray, or hospital edge servers
- Power efficiency for continuous operation in constrained environments

Brain CT/MRI Multi- slice Tumor Detection
The trade-off between model sophistication and clinical practicality represents the primary bottleneck in the adoption of medical AI today.
MCW’s Role: Making MONAI Edge-Ready
At MulticoreWare, we bring deep expertise in hardware-aware optimization, model compression, and regulatory-grade deployment. Our work turns heavyweight MONAI pipelines into real-world clinical AI systems.
- Model Optimization for Edge Devices
- Quantization (INT8, BF16, mixed precision) for speed and size reduction
- Compression, Pruning & Graph tuning to streamline computation paths
- Hardware-specific acceleration across NVIDIA Jetson, Intel OpenVINO, Qualcomm SNPE, AMD Vitis AI, and even custom ASICs to ensure peak performance on any target.
- Target use cases: Enabling AI on portable ultrasound probes, mobile X-ray units, and low-power diagnostic endpoints.
- Retraining & Customization for Clinical Workflows
Medical AI must balance generalization with domain specificity. We enable the adaptation of MONAI models with hospital-specific data, imaging protocols, and patient populations:
- Transfer Learning & Domain Adaptation – fine-tuning with local datasets for improved relevance.
- Self-supervised learning (Leveraging unlabelled dataset) for scarce annotations
- Federated learning to preserve patient privacy across hospitals
- Compliance-aware validation (FDA, CE, ISO 13485)
Case in point : Retraining a prostate MRI segmentation model with just 100 annotated scans from a regional hospital improved Dice score from 0.72 to 0.89, thanks to domain-specific augmentation and MONAI Auto3DSeg pipelines.
Real-World Applications of Optimized MONAI Models
Point-of-Care Imaging
Real-time inference on portable ultrasound and mobile CT in low-resource environments
Pathology
High-resolution slide analysis using optimized vision transformers within hospital IT systems
Neuro & Cardio
Accelerated 3D segmentation of brain tumors or cardiac chambers on hospital edge servers
Agentic AI Assistants
MONAI + Vision-language-enabled tools supporting radiologists with interactive diagnostic suggestions
Why MulticoreWare?
At MulticoreWare, we go beyond accelerating AI, we transform SOTA medical imaging models into efficient, reliable, and deployable solutions for real-world clinical environments. Our expertise ensures that AI developed in research labs can perform at the edge, where it matters most – in hospitals, diagnostic devices, and point-of-care systems.
- MCW has optimized over 1000+ SOTA AI models (including CNNs, Transformers, Generative AI) for efficient edge deployment across diverse domains.
- Deep experience with industry-standard frameworks like MONAI, nnU-Net, TorchIO, and advanced hybrid workflows involving Vision-Language models.
- MCW delivers Edge-ready optimization for CPU, GPU, DSP, and NPU architectures, covering both NVIDIA and non-NVIDIA based SOCs & Accelerators.
- Our proven success includes advanced techniques like Post-Training Quantization (PTQ) and Quantization-Aware Training (QAT), leveraging tools such as AIMET, Ryzen AI, TensorRT, and OpenVINO etc., for robust, real-world deployments.
Conclusion: From Foundation Models to Deployable Care
Frameworks like MONAI have opened new possibilities in medical imaging AI. However, without edge-ready optimization & precise hardware tuning, many promising models risk remaining confined to the lab. This is where MulticoreWare’s role becomes pivotal: transforming compute-heavy Medical Imaging AI Models into real-time, clinically deployable AI systems that seamlessly integrate within the demanding constraints of healthcare delivery. The true future of medical imaging AI will not solely be defined by accuracy on benchmark datasets, but by its ability to run efficiently and reliably in the hands of clinicians and patients who need it most. And that is precisely where MulticoreWare is leading the way.